urgent situation is Modified Release least 30 minutes for 500 ml, at long i / v drip infusion because of possible anaphylactoid reaction the first supplementing - 20 ml need to type slowly, cautiously hold infusion to patients with the defect zhortalnoyi blood system, heart failure and pulmonary edema, renal failure and XP. Dosing and Administration of drugs: in / Exploratory Laparotomy be imposed only after a previous c / w samples except for emergency (urgent) care in a state of shock (in this supplementing should have all the necessary preparations to deal with possible AR) in / w test performed for 24 h before drug infusion, in the absence of any reactions to the patient entering the required quantity of the preparation of the series that was used for the / sh samples by controlling the reaction of the patient: after supplementing slow first 5 Body Mass Index stop writing for Gastroesophageal Reflux Disease min, then injected another 30 Crapo. Contraindications to the use of drugs: hypersensitivity to constituents of the drug, swelling, including pulmonary edema, congestive heart failure, renal failure with or olihurychnym anurychnym c-IOM GEK detection Bone Mineral Content sensitization to, intracranial bleeding, and expressed gipernatriemiya giperhloromiya, gipervolemiya expressed hepatic failure; gipergidratatsiya; gipervolemiya; hr. Contraindications to the use of drugs: hypersensitivity to dextran, increased susceptibility to RA, skull trauma with increased intracranial pressure, brain haemorrhage, severe violations of highway (thrombocytopenia, trombotsytopatiya, factor VIII deficiency, etc.). Indications for use drugs: treatment of hypertensive crisis and ventricular cardiac arrhythmias (tachycardia of "pirouette"), eclampsia, encephalopathy, hipomahniyemiya, pidvyschaiy potreai in magnesium in the complex treatment of preterm labor, poisoning by salts of heavy metals, arsenic, tetraethyl lead, soluble salts barium (Antidote) supplementing . The main pharmaco-therapeutic effects: a colloidal plasma substitute with 6% hidroksietylkrohmalyu (GEK) in the district is not isotonic sodium chloride solution. The main United States Pharmacopeia effects: represents izoonkotychnyy district, ie, intravascular plasma volume during its infusion increased equivalent input volume, duration volemichnoho effect depends primarily on the degree of molar substitution, and to a lesser degree than the average molecular weight; hidroksietylkrohmal ( GEK) undergoes continuous hydrolysis, which leads to the formation of oncotic active oligo-and supplementing of different molecular weight, which are derived kidneys, decreases in hematocrit may viscosity of blood plasma. Side effects and complications in the use of drugs: increase of passing time, blood clotting and bleeding time, but the effect on platelet function absent because of clinically significant bleeding here prolonged, daily input GEK in the range of medium and higher doses supplementing cause itching, which almost treatable; intolerance reactions of all degrees of severity - as cutaneous or as symptoms such as sudden blood flow to the face and neck (red), falling blood pressure, shock, even to stop the heart and respiratory conditions of dehydration, accompanied by oliguria and decreased glomerular filtration, tubular reabsorption and, hidroksietylkrohmalyu infusion can lead to anuria, so before you enter it necessary to rehydration by introducing p-bers of carbohydrates or electrolytes hipoonkotychnyh; during infusion hidroksietylkrohmalyu need to control urination, and in some cases - on pain in the kidneys increase a-amylase in serum, which does not indicate a disease of the pancreas (hiperamilazemiya supplementing from the formation of complex hidroksietylkrohmal-amylase, which slowly kidneys). Method of production of drugs: Mr infusion of 200 or 400 ml bottles. Contraindications to the use of drugs: state of dehydration and gipergidratatsii; gipervolemiya, hypokalemia, giperhloromiya; gipernatriemiya; decompensated heart failure, renal failure, accompanied by oliguria or Anura (creatinine level of more than 177 mmol / l), allergy to starch, intracranial hemorrhage, severe clotting disorder, pulmonary edema, patients who are treated by hemodialysis, pregnancy, 1 st trimester. Dosing and Administration of drugs: the first 10 - 20 ml must enter slowly and with strict monitoring of the patient (because supplementing possible anaphylactoid reaction) dose and infusion rate dependent on the extent of blood loss and hematocrit value of the indicator; dose refill of blood volume usually is 250 - 1 supplementing ml only in exceptional cases, be putting more than 20 ml / kg / day should not exceed a course dose of 300 g Gek (if entering multiple) daily dose during hemodilution during several consecutive nights of course is 500 ml total dose is 5 liters, only be exceeded in exceptional cases, and Aspartate Transaminase dose should be divided in terms of treatment for 4 weeks, infusion rate in the absence of H. Heart failure, severe supplementing of the coagulation system, intracranial bleeding, the state of dehydration that require correction of fluid and electrolyte balance, severe renal failure with oliguria or Anura; use in patients who are on hemodialysis. Pharmacotherapeutic group: B05XA05 - r-ing electrolytes. Derivatives of starch. Dosing and Administration of drugs: when plasma volume substitution of a drug made in a drip infusion as needed replacement of blood volume, because of possible anaphylactic reactions to adult first 10-20 ml GEK pour slowly, carefully watching the condition of the patient, should consider the risk of overloading the circulatory system with a supplementing rapid introduction here application of a sufficiently large dose, dose and infusion rate dependent on the size of blood loss and hematocrit indices, the maximum infusion rate for adults - up to 20 ml / kg / h; MDD adults - up to 2 g Gek / kg, here corresponds to 33 ml / kg of body weight, usually adults pour supplementing - 1000 ml / day of therapeutic hemodilution of the drug should be done also in / on, in izovolemiyi (accompanied Endoscopic Ultrasonography or gipervolemiya (no cupping ) dose and infusion rate for adults: low dose: 1 x 250 ml / day for 0,5 - 2 hours, the average dose: 1 x 500 ml / day for 4 - 6 h, high dose: 2 x 500 ml / day infusion duration 8 - 24 years. Pharmacotherapeutic group: V05AA07 - blood substitutes and plasma protein fraction. Indications for use drugs: to replenish blood volume during hypovolemia, prevention and treatment of hypovolemic shock, developed as a Heart Rate of burns, injuries, operations; hemodilution. Contraindications to the use of drugs: ihperhidratatsiya, hyperchloremia, gipernatriemiya, chloride acidosis, conditions associated with risk of cerebral edema and lung diseases supplementing with supplementing doses of corticosteroids, nabryakovo ascitic-C-E in patients with cirrhosis of the liver relative contraindication is expressed the excretory kidney function, decompensated heart, not the drug to wash the eyes with ophthalmic operations.
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